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The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance epub ebook

by Nessa Carey

The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease, and Inheritance epub ebook

Author: Nessa Carey
Category: Medicine
Language: English
Publisher: Columbia University Press; 1 edition (March 6, 2012)
Pages: 352 pages
ISBN: 0231161166
ISBN13: 978-0231161169
Rating: 4.2
Votes: 448
Other formats: lit docx mobi azw


Nessa Carey is a visiting professor at Imperial College in London and currently works in the biotechnology and . That being said, it was incredibly helpful in updating my understanding of this field.

Nessa Carey is a visiting professor at Imperial College in London and currently works in the biotechnology and pharmaceutical industries, where she has specialized in epigenetics for nearly a decade. As a biology major in the ‘90s, this field was so nascent that it was barely addressed, let alone studied thoroughly.

Nessa Carey takes us on a lively and up-to-date tour of what's known about epigenetic mechanisms and their implications for . I liked how Nessa Carey laid out the book. She starts with a history and some examples of epigenetics

Nessa Carey takes us on a lively and up-to-date tour of what's known about epigenetic mechanisms and their implications for ageing and cancer. Laurence Hurst, University of Bath Focus Magazine). She starts with a history and some examples of epigenetics. She then discusses cells and how they work and how epigenetics is contributing to understanding diseases such as cancer and Alzheimer’s. She looks at why identical twins are not truly identical at the cellular level and how psychological trauma at an early age can affect us.

The Epigenetics Revolution book. Goodreads helps you keep track of books you want to read. Start by marking The Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Disease and Inheritance as Want to Read: Want to Read savin. ant to Read.

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity.

Now more than ever, biology has the potential to contribute practical solutions to many.

When you do things from your soul, you feel a river moving in you, a joy. ― Rumi. A New Biology for the 21st Century. 6 MB·23,499 Downloads·New! Now more than ever, biology has the potential to contribute practical solutions to many.

This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more.

But this book, subtitled: "How modern biology is rewriting our understanding of genetics, disease .

But this book, subtitled: "How modern biology is rewriting our understanding of genetics, disease and inheritance", is an attempt to put matters straight. Epigenetics is what happens when genes are actually in action: in the growth of the foetus, in responding to hormones and environmental stress, to learning, to maturation at puberty. Nessa Carey, science director for a leading epigenetics biotech company and a lecturer in genetics at Imperial College, writes brightly and humanely and is full of optimism for this exciting new dawn – both for the deep understanding of life and the potential for medical applications.

How Modern Biology Is Rewriting Our Understanding of Genetics Epigenetics Revolution Disease and Inheritance, Epigenetics Revolution: How Modern Biology Is Rewriting Our Understanding of Genetics, Epigenetics Revolution How Modern Biology Is Rewriting Our Understanding of Genetics Disease and Inheritance, Disease and Inheritance: Nessa Carey: 9781848313477: Books .

The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years

The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all – and in the surprisingly near future. Announce URL: udp://tracker.

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics.Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.
Reviews (7)
Cells
This is a fine introduction to the topic by an extremely knowledgeable researcher. Carey tries to make it all very accessible to the novice, but in fact it presupposes a fair amount of understanding of molecular biology, especially of how DNA and RNA work, and at least a rudimentary understanding of protein folding and heredity.
I felt there was too great an emphasis on epigenetic causes of human diseases, about which fairly little is known (except for a few rare but well-explored cases). Therefore, I only skimmed the last few chapters.
I read this book and also took a Coursera online course in epigenetics, but I still have no clear idea about the relationship between genetics and epigenetics as applied to inheritance patterns. I cannot imagine how to add epigenetic dynamics to the biological models I work with, or if they make any difference at all to population biology.

Tam
This is my first book on Epigenetics and it’s fascinating how different situations, actions, or experiences in our lives can affect our cells. Events that happened to our parents, grandparents, and so forth can also affect our cells in ways science is just starting to understand. I liked how Nessa Carey laid out the book. She starts with a history and some examples of epigenetics. She then discusses cells and how they work and how epigenetics is contributing to understanding diseases such as cancer and Alzheimer’s. She looks at why identical twins are not truly identical at the cellular level and how psychological trauma at an early age can affect us. She finishes the book with what we can expect to see in the future from the field of Epigenetics.

I learned a lot from this book and want to learn more about this topic. I did find it difficult to stay engaged, partly because of Carey’s abundant use of adverbs, and partly because I’m not well versed in biology. Maybe if I had a better basic understanding before going in – it’s been a long time since I took a college biology course – it would’ve been more engaging for me. Overall a great introduction to the field.

Granijurus
If you are looking for a comprehensive introduction to the science of epigentics, this will serve you well. It was a relatively easy and enjoyable read.

The criticism of its intended audience being unclear is fair. At times, it seems to be aimed at a rather lay audience with slightly odd analogies that over simplify almost to a fault. A few pages later, jargon and technicalities are tossed around that definitely require a solid background in biology to follow with any ease. This has the discordant effect of making the simplistic analogies seem even more odd. It can’t seem to decide if it expects you to remember only basic high school biology or if it prefers you’ve had at least a couple of undergraduate level courses in molecular biology and genetics.

That being said, it was incredibly helpful in updating my understanding of this field. As a biology major in the ‘90s, this field was so nascent that it was barely addressed, let alone studied thoroughly. As a teacher of AP Bio in high school today, I needed an update on vertebrate gene regulation in order to be able to competently address the topic in my classroom. This book provided exactly that. While I won’t be teaching most of the advanced details in this book, I will be adjusting a few critical things to ensure alignment with today’s knowledge.

Even better, it reminded me why I have always found genetics so fascinating. It’s even more so now than it was 25 years ago. As so often happens in emerging fields, each intriguing answer leads to dozens more questions. If you think the way a basic prokaryotic operon works is pretty cool, learning about mammalian epigenetic gene regulation will make your brain geek out with intellectual joy.

Acrobat
Very nicely written layman level intro to Epigenetics. Great analogies, good exposition, good emphasis about explaining why discoveries are important are unexpected.

Read it as an informal textbook to an academic class in Epigenetics. Probably got 33% of all the learning from the book and 67% from the class, and I have a suspicion the the basic lessons of the book will stick more than the forest of class details about what protein acetylates what unit of the histone.

Would possibly be nice to expose a little more of the molecular detail, without frightening horses and small children.

Samutilar
I had to read excerpts from this book for a graduate level biology class. I was so interested in learning more about how epigenetics is changing our understanding of inheritance that I had to purchase it and read more. This should be required reading for all "older" biology teachers. Highly recommended!

Brannylv
I have enjoyed the book, and I would definitely recommend it to novices and experts. I am a DNA methylation professional, I work on molecular mechanism of DNA methylation. I bought the book to have one place reference for the phenotypic aspects of epigenetics. I think that the author did an excellent job of balancing the text for different types of readers. The author gives the names of the researchers that did some key discoveries, so the interested reader can always go to google.scholar and pubmed for the original publications. The simple language, numerous comparisons and explanations makes this book readable to the people without expertise in epigenetics, but also to an average graduate with BSc degree.

The book is not for people interested in molecular aspects of DNA methylation, but it does not need to be, since such text would not be for a wide audience. My only critique would be that the author should add few more figures, that could make the text bigger pleasure to read and browse. If there are about 10 more drawings in the text I would give it full five stars. I have no doubt that with rapid development of epigenetics, this book will come in newer editions. With few additional drawings, it will be a five star read. One missing figure could be changes in DNA methylation through embryonic development and gametogenesis. Congratulations to the author, Cheers to all readers.

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